Sunday, June 28, 2009
Essential #5 of Your Diabetic Foot Team: Be Prepared to Surgically Drain Infection or Remove Gangrene.
Today we will discuss essential skill number five:
5. If necessary, be prepared to surgical drain any infection or surgically remove any dead tissue (gangrene) at the bedside (debridement).
This is a topic that is not for the squeamish. So prepare yourself.
All amputations in diabetic patients start out as some type of foot infection. The foot infection becomes worse, the bacteria rages out of control, and gangrene sets in. Gangrene is a scary term but simply means death of tissue. Dead tissue happens to be a fabulous medium for bacteria.
This skill is the one most typically referred to as “limb salvage.” If you look up the word “salvage” in the dictionary, you will find “property saved from destruction in a calamity (as a wreck or fire).”
Only by aggressively removing infected and dead tissue can the destruction of a diabetic foot infection be halted.
Emergency surgery is very common in treating diabetic foot infections. The very best way to treat a bad diabetic foot infection is by physically removing the infection…not by giving antibiotic pills. This means opening any area of infection to remove all of the bacteria. The infected compartment of the foot has to be irrigated. This is in addition to antibiotics, not instead of antibiotics.
Your team must be prepared to perform emergency surgery if the infection is bad enough that it is deemed a “limb threatening infection.” You have to keep in mind that the diabetic patient has an immune system that is weak. Because of this one is often unable to fight off an infection.
You have to also remember that poor circulation in the feet and legs (called peripheral arterial disease) is very common in diabetics. Most people with diabetes who are at high risk of a diabetic foot or leg amputation suffer from problems with the circulation in their legs and feet. Any antibiotics are delivered through the bloodstream. So poor circulation means poor delivery of the infection fighting antibiotic drugs.
In 2005, there was a research paper published in medical journal that discussed the risk of hoping to avoid surgey in diabetic foot infections. The article was entitled “Osteomyelitis of the Foot and Toe in Adults Is a Surgical Disease Conservative Management Worsens Lower Extremity Salvage.”
Osteomyelitis is the medical term for a bone infection. The point of this paper was to stress to physicians that hoping for the best and just giving antibiotics does not work. In fact, as the title suggests, that actually makes things worse. Surgery is necessary in order to save a leg from a diabetic foot infection.
Diabetes is a scary disease. Diabetic foot infections likewise can be simple or complicated. In either case, an evaluation is warranted given the potential for the loss of a limb. This should never be taken lightly. Keep in mind that most diabetic foot ulcerations do not need to end up as an amputation.
Although all of this talk about surgery, infections, gangrene and amputations can certainly be alarming, you should remember that your diabetic treatment team is on your side. As long as they are vigilant, you should be able to avoid any of these complications. Make sure you get an evaluation early whenever you notice an open sore. And if necessary, evaluate your team based on these criteria.
Diabetic foot amputation is preventable. Live long and enjoy your life!
Dr. Christopher Segler is an award winning diabetic foot specialist. Although he has performed diabetic foot amputations, he still believes that diabetic foot amputations result from the dismal performance of a failing health care system that prevents adequate patient education. It is his passion to teach strategies that can stop diabetic amputations. You can learn more by requesting your FREE report “No Leg Left To Stand On: The Secrets Insurance Companies Don’t Want You To Know About Diabetic Foot Amputation” at http://www.ineedmyfeet.com.
Friday, June 12, 2009
Your Diabetic Foot Treatment Team: Why they must evaluate the depth and character of the wound.
Today we will discuss essential skill number four
4. Evaluate the depth and character of the wound. (Perform a wound assessment that includes both staging/grading of infection and ischemia.)
Open sores on the feet of diabetic patients are very common. These of course are referred to as diabetic foot ulcerations. Not every diabetic foot ulcer will lead to an amputation. Having said that, most diabetic foot or amputations start as a diabetic foot ulcer.
Because of this, it is extremely important for you ta make sure your diabetic foot treatment team thoroughly evaluates any diabetic wound.
Anytime you have a serious medical condition, the first question is…how bad is it? For example if you have cancer, you want to know what stage of the cancer. The stage of the cancer will tell you the extent of the spread and likelihood that you will live or die.
In the same way, staging a diabetic foot ulcer can determine whether or not your foot will live or die. Determining the wound stage will help to determine whether or not you will need to be hospitalized, have intravenous antibiotics, surgery, or even an amputation.
Before describing the staging process, let me caution you as a patient. It is my long-held belief that medical school is a way for doctors to teach student doctors how to lose their ability to communicate with patients.
Classification systems are a very good example of this. In my residency (that had a heavy focus on diabetic foot training), my director understood this more than most. In our surgical conferences if a student or resident doctor mentioned a classification of any condition, Dr. Young would always demand that they explain exactly what that classification meant. This is a vital skill for clear communication. It shows that the doctor can know and explain what is really going on.
Many doctors lose disability. They become so familiar with the technical language and classification schemes, that they are simply unable to describe in simple terms what they see when they evaluate a wound, an illness or a condition.
So without giving you all the specifics about each of the different classification schemes, we will explain what the components are that need to be evaluated and why each is important.
The first component of a diabetic foot ulcer (open wound) classification system that should be evaluated by your treatment team is the size of the hole. It doesn’t really matter how big it is across your foot, but it doesn’t matter how deep. The skin on the foot is very thin and when a diabetic ulcer gets deeper, tendons, ligaments, and bone can become exposed and damaged or infected. Bones and joints that is clearly exposed to the external world through an open diabetic wound can only very rarely be saved.
Not surprisingly, as the wound becomes deeper. The condition is taken much more seriously. In general, skin will not just grow in and cover exposed tendons and ligaments, joints or bones. Action must be taken. In many cases this means surgery. A hope and a prayer is rarely enough.
Once your team has decided how deep it (and what tissues are exposed through the wound) they should next determined whether or not infection is present. This is usually not difficult. Any experience treatment team should be able to determine easily if the wind is infected or not. By definition, if your team cultures the wound, they believe that it is infected. See essential number three.
Next they should determine whether or not there is sufficient blood flow to heal the wound. Poor blood flow to an area is referred to by doctors as “ischemia.” You have to remember that any antibiotics are delivered to the foot through the bloodstream. If the blood flow is poor, the antibiotics can’t even get to the site where the battle is taking place. In addition, there is very little chance of the wound healing without good blood flow.
If the ischemia (or poor circulation) gets bad enough, gangrene can set in. Gangrene is nothing more than death of the tissue. It is often related to infection. Obviously is critical to your team and evaluates the blood flow to your feet whenever you have a diabetic foot wound.
If you have ischemia and an open sore on a single toe, and your treatment seem decides to amputate that toe, it is possible that the blood flow is so bad that the amputation site won't heal. This could create an even larger problem hole in your foot. It is a very basic tenant of diabetic foot surgery that the level of amputation must have sufficient blood flow to heal. Otherwise you may end up with each of your little piggy’s going to market one at a time.
By evaluating the depth of the wound ( including skin, tendon, joint, and bone involvement), presence or absence of infection, and presence or absence of ischemia, a much more realistic prognosis can be determined. All of these factors must be considered in order to determine whether or not the wound is likely to heal without hospitalization and/or surgery.
If you have a diabetic foot ulceration that is being treated without evaluating all of these factors, it might serve you well to seek a second opinion. You should also feel you have the liberty to ask your doctor whether or not you have an infection, any ischemia, or exposed tendon or bone. This is your right. Expect your doctor to explain what is going on.
Beware of doctors who feel you don’t deserve answers.
Diabetes is a complicated disease. Diabetic foot problem likewise can be simple or complicated. In either case, an evaluation is warranted given the potential for the loss of a limb. This should never be taken lightly. Keep in mind that most diabetic foot ulcerations do not need to end up as an amputation.
Although all of this talk about amputations can certainly be frightening, you should remember that your diabetic treatment team is on your side. As long as they are vigilant, you should be able to avoid any of these complications. Make sure you get an evaluation early whenever you notice an open sore. And if necessary, evaluate your team based on these criteria.
Amputations are preventable. Live long and enjoy life!
Dr. Christopher Segler is an award winning diabetic foot specialist. Although he has performed diabetic foot amputations, he still believes that diabetic foot amputations result from the dismal performance of a failing health care system that prevents adequate patient education. It is his passion to teach strategies that can stop diabetic amputations. You can learn more by requesting your FREE report “No Leg Left To Stand On: The Secrets Insurance Companies Don’t Want You To Know About Diabetic Foot Amputation” at http://www.ineedmyfeet.com.
Monday, June 8, 2009
Your Diabetic Foot Treatment Team: Why they should obtain wound cultures to determine if any dangerous organisms such as MRSA are present.
Today we will discuss essential skill number three
3. Obtain wound cultures to determine if any dangerous organisms such as MRSA are present. Use appropriate culture techniques.
The primary reason that a person ends up with a diabetic foot amputation is because of a poor blood supply and uncontrolled infection. When ever a diabetic foot ulceration (open sore) develops, bacteria that is normally growing on the skin will live within the wound.
Doctors call this colonization. Colonization is what a normal process. Your entire skin is colonized with bacteria. In most instances, colonized bacteria do not cause harm or disease. The difference between colonization and infection is that one is a normal process and another causes harm.
One definition of infection is “to do well in internally endoparasitically as opposed to externally.” A parasite always lives at the expense of its host. When bacteria in an open wound on a diabetic foot begins to invade the tissue, rather than just living on the surface a diabetic foot infection begins.
In order to remove any infecting bacteria it is important to differentiate the organism causing the infection from other organisms that are normally growing on the skin and may not be causing any harm. The most reliable way to differentiate these two groups of bacteria is by obtaining a wound culture.
A wound culture is a process whereby a doctor obtains a sample of infectious material and places it in an artificial medium, where it will grow. The basic idea, is to take samples of the bacteria in the wound and transfer them to a petri dish and place them in an incubator. The bacteria will then start to grow.
If several samples of different antibiotics are placed with in the petri dish and marked, the bacteria will not grow, near the antibiotics to which they are susceptible. This is how doctors determine which antibiotics are likely to kill the bacteria and remove the infection from a diabetic foot.
In order to remove an infection, you must take the appropriate antibiotics. This can only be determined accurately with a culture.
Not only is it important to take a wound culture and make sure that a diabetic foot infection is being treated correctly, timing is also important. It takes a couple of days for cultures to determine which antibiotics are going to be effective. Because of this, most diabetics with an infected open sore will be started on antibiotics that are probably going to work. It is critical that the wound culture is taken before these antibiotics are given. Once antibiotics have been given, but when cultures become unreliable.
If the diabetic foot infection is not treated with the right antibiotics, they can take much longer to remove the infection. Most antibiotics are processed and removed from the bloodstream by the kidneys. Diabetics are at high risk for kidney damage. Often times when someone who is a diabetic takes antibiotics for a long period of time, they can damage the kidneys further. This can lead to complete renal failure, which places the patient on dialysis. A diabetic patient who has had kidney failure will die without dialysis to remove impurities from the blood.
This being the case is understandable why it is important to make sure that any antibiotics taken are going to the effective and only administered for the shortest period of time.
Whenever you go to the emergency room or see a doctor because you believe that you have an infected diabetic foot ulceration, you must insist that cultures are obtained before you start any antibiotics. This will help speed your healing, minimize the chances of any kidney damage, and reduce the risk that you will end up with a diabetic leg amputation.
Keep in mind that early treatment is key. If you believe that you are developing a diabetic foot infection, you should seek treatment immediately. No matter what time of day or night. You should call your treating physician and explain to them, what is happening so that treatment can begin right away.
This is why it is so important for everyone with diabetes to have a doctor that they feel they can call at any hour to discuss their concerns. In most cases, a short discussion can help you determine whether or not, you need to get out of bed and go to the emergency room or if this is a smaller issue, or if it can wait until the next day.
No issue is too small to discuss with your diabetes doctor. Diabetics are at extraordinary risk for having what seems like a minor problem end up as a life-changing amputation. Amputations are preventable.
Dr. Christopher Segler is an award winning diabetic foot specialist. Although he has performed many diabetic foot amputations, he believes that diabetic leg amputations result from a failing health care system and inadequate patient education. It is his passion to teach strategies that can stop diabetic amputations. You can learn more by requesting your FREE report “No Leg Left To Stand On: The Secrets Insurance Companies Don’t Want You To Know About Diabetic Foot Amputation” at http://www.ineedmyfeet.com.
Monday, May 25, 2009
Evaluating the Competency of Your Diabetic Foot Treatment Team: Essential Skill #2: Testing for Diabetic Peripheral Neuropathy in the Feet.

Evaluating the Competency of Your Diabetic Foot Treatment Team: Essential Skill #2: Testing for Diabetic Peripheral Neuropathy in the Feet.
In these discussions, we discuss each of the 7 essential skills that your diabetes treatment team must use in order to help you prevent an amputation related to your diabetes.
Today we will discuss essential skill number two.
2. Test for neuropathy to help determine the risk of ulceration and amputation.
In the simplest of terms, nerves are the wiring system of the body. They carry information from the outer reaches of the body (such as the hands and feet) all the way back to the brain where this information is processed. One thing that wires and nerves have in common is that they both transmit electrical signals. However, it is probably not a surprise that by comparison, electrical wiring system is significantly simpler than a nervous system.
There are a number of processes that happen within the body that can affect the function of nerves. In the diabetic patient in particular, this includes the way the body is using insulin, levels of blood sugar, levels of circulating lipids (or fats in the blood), blood supply to the nerves themselves, and energy metabolism with in the nerve cells that make up an individual nerve.
Although there are many different processes which can damage nerves, high circulating levels of blood sugar are likely the most damaging. In the United States, diabetic peripheral neuropathy (nerve damage in the feet related to high levels of blood sugar) is the most common type of sensory nerve damage.
Although the nervous system is very complex, checking for nerve damage can be remarkably simple. The most reliable test in order to evaluate whether or not a diabetic patient is at risk of developing neuropathic ulceration that might lead to hospitalization or amputation of the leg can be done in only a few minutes and at very low cost. Because of this, it is absolutely inexcusable that a doctor treating a diabetic would not evaluate the function of the nerves in the feet.
In addition to being low cost and simple to perform, there is one test that is the most useful of all exams in determining whether or not a patient is at risk of developing a problem that might lead to a diabetic foot amputation.
This test is called the Semme’s-Weinstein 5.07 monofilament test. In this test, a 5.07 mm diameter monofilament wire is used to apply precisely 10 grams of pressure to the skin of the diabetic foot in order to determine whether or not
the patient has what is known as “protective sensation”.
During this test, the doctor will ask you to close your eyes. He or she will then touch different parts of your feet with this monofilament asking you to say “right” or “left” whenever the doctor touches either of your feet.
If you can feel every area where the doctor touches your feet, you are at low risk of developing a diabetic foot ulceration that might lead to amputation.
If you do have some loss of sensation, the damage is usually at the ends of the longest nerves in the body. The longest nerves of course happen to go from the spinal cord all the way down the legs and out to the end of the toes. Because of this, the damage seems to appear in what doctors call a “stocking glove distribution pattern.” This means that the damage occurs starting the end of the toes and will usually stop in the same area on both feet as if one has rolled socks on to both feet at the same time.
For example, someone may have lost all of the sensation in the toes, but has all of the station present in the ball of the foot. This means that the patient is at risk of having an open sore develop in the toes but less likely in the midfoot or ball of the foot.
Because this can get worse over time, it provides a good baseline to determine if the diabetic foot problems are staying the same or getting worse.
The implications of this test are that if you have lost “protective sensation,” you are at high risk of starting to develop a blister and not being able to feel that there is a problem. The patients that have this sort of nerve damage will oftentimes step on foreign objects such as splinters, thumbtacks, or slivers of glass and never even noticed that anything has happened. It is this type of open sore that can rapidly develop into an infected diabetic ulceration and later lead to a diabetic foot amputations.
There are a number of other tests that can be used to evaluate the function of the nerves in the diabetic foot. Simply touching a specific type of vibrating tuning fork to the feet and ankles can get a great deal of information about early nerve damage that may be present but not yet concerning for the kind of damage that can lead to open sores.
Other screening tests that your doctor might use include checking hot/cold sensation, two-point discrimination, and evaluating light touch sensation. Nerve conduction velocity exams are more invasive tests and should be reserved for those with indications of problems such as tarsal tunnel syndrome.
Even if there is nerve damage, the open sores that result primarily from existing nerve damage are still mostly preventable. It just requires a little extra vigilance on the part of the patient and the doctor.
If there is only one screening test is performed your doctor evaluating your risk of foot problems that could lead to an amputation, it is the SWMF 5.07 test. For this reason, you must make sure that your diabetic foot doctor checks your feet initially to determine your risk of developing the sort of problems.
Only then will you know whether or not you are at imminent risk of and amputation.
Dr. Christopher Segler is an author, inventor and award winning diabetic foot surgeon. After discovering how diabetic leg amputations resulted from inadequate patient education, it became his passion to teach strategies to stop diabetic amputation. You can learn more by requesting your FREE report “No Leg Left To Stand On: The Secrets Insurance Companies Don’t Want You To Know About Diabetic Foot Amputation” at http://www.ineedmyfeet.com.
Saturday, May 23, 2009
Evaluating the Competency of Your Diabetic Foot Treatment Team: Essential Skill #1: Assessing the Circulation to the Feet and Legs.
Today we will discuss essential skill number one.
1. Assess the circulation (blood flow) to the feet and legs to determine the risk of gangrene.
There is a long-held joke among podiatrists that the only function of the heart is to pump the blood to the feet. The suggestion with this is the over-emphasis on the importance of delivering oxygenated blood to the tissues in the feet in order to keep a diabetic patient from developing a problem that might lead to premature death.
It is a well-researched fact that diabetics develop problems with their blood flow at a much faster rate than other people. This happens everywhere in the body. Through the process known as atherosclerosis (or hardening of the arteries) blood vessels become lined with plaques that are deposited over time. As these deposits increase, the diameter of the inside of the blood vessel becomes smaller and smaller, effectively decreasing blood flow.
This has been well documented in the coronary arteries of diabetic patients. We know that if you take two patients (one who is diabetic and one who is not) who are otherwise identical, the patient who has diabetes is four times more likely to have a heart attack. In large part this is due to the accelerated rate of atherosclerosis.
This same process occurs in the arteries of the feet and legs. Because of this process, the blood flow to the feet is dramatically reduced over time. Without blood flow, there is no oxygen delivered to the tissues. Without oxygen tissues die. Gangrene is nothing more than death of the tissue. Gangrene is one of the leading causes of amputation among diabetic patients.
With all of this is in mind, it is very easy to understand why your doctor must assess the blood flow to your feet. There are many ways to do so.
The simplest tests (and those most likely to be performed by any doctor evaluating a diabetic patient’s blood flow to the feet) involve a simple physical examination. During this exam, the doctor will likely attempt to feel the pulses behind the inside of your ankles (posterior tibial artery pulses) and on the tops of your feet (dorsalis pedis artery pulses). If the clinician is able to feel these pulses easily, the chances of developing extraordinarily bad blood flow known as critical limb ischemia are very small.
If the clinician is unable to feel these pulses, a hand-held Doppler device will typically be used in order to further evaluate the blood flow. This is a simple easy to perform test that does not cause any discomfort to the patient and can give a great deal of information about the state of blood flow.
More extensive tests are sometimes needed. Other tasks include transcutaneous oxygen pressure measurements (Tcp02), toe Doppler wave form analysis and toe pressures, and arterial duplex ultrasound.
If the results of these studies show severely compromised blood flow, it may be necessary to perform other more expensive exams including computed tomography angiography or magnetic resonance angiography. These are tests that use either CT scans are MRI evaluations to closely evaluate the state of blood flow in the feet and legs. They can provide an extraordinary amount of information but are oftentimes difficult to get approved by insurance companies due to their extraordinary cost.
The combined results of all of these exams are considered closely with the patient’s history, other physical exam findings and symptoms. In many cases all that is needed is continued monitoring of the patient. However, if findings warrant rapid intervention, it may be necessary to have an angioplasty or arterial stent placement in the leg in order to restore blood flow by a vascular surgeon. Other times an open arterial bypass is sometimes needed.
One thing that is clear is that delays in evaluation of the blood flow to the feet and legs can create huge problems. The most obvious of these would be development of gangrene as a result of critical limb ischemia that would make an amputation necessary.
The bottom line is that any doctor evaluating a diabetic patient should check (at the bare minimum) the pulses in both feet. If you see your diabetic doctor and the he/she does not ask you to take off of your shoes to evaluate the pulses in your feet, you should immediately find another doctor.
Dr. Christopher Segler is an author, inventor and award winning diabetic foot doctor. After discovering how amputations resulted from a failing health care system, it became his passion to teach strategies to stop diabetic amputation. If you have diabetes, you can learn more by requesting your FREE report “No Leg Left To Stand On: The Secrets Insurance Companies Don’t Want You To Know About Diabetic Foot Amputation” at http://www.ineedmyfeet.com.
Friday, May 22, 2009
7 Essential Skills Your Diabetes Treatment Team Must Have
We know that diabetes worldwide is becoming an epidemic. In the United States the growing population of diabetic patients is now almost 26 million. Because more and more doctors are being forced to take care of diabetic patients, guidelines are needed to provide guidance and standards to help all treating medical professionals understand the steps to take and ensure their patient doesn’t unnecessarily wind up with a diabetic below knee amputation.
This article cited seven essential skills that are absolutely necessary in order to provide the very best outcomes in terms of diabetic limb salvage.
1. Assess the circulation (blood flow) to the feet and legs to determine risk of gangrene.
2. Test for neuropathy to help determine risk of ulceration and amputation.
3. Obtain wound cultures to determine if any dangerous organisms such as MRSA are present. Use appropriate culture techniques.
4. Evaluate the depth and character of the wound. (Perform a wound assessment that includes both staging/grading of infection and ischemia.)
5. If necessary, be prepared to surgical drain any infection or surgically remove any dead tissue (gangrene) at the bedside (debridement).
6. Be prepare to evaluate the cultures and change the antibiotics to most effectively fight the bacteria causing the infection.
7. Continually re-evalauet after surgery, noting the risk of recurring problems in order to avoid re-ulceration, re-hospitalization, and re-amputation of the diabetic foot.
Over the next week or so, we will discuss each of these in depth.
Dr. Christopher Segler believes diabetic amputations are preventable. He teaches strategies that help his clients avoid amputation. He is also and award-winning diabetic foot surgeon, inventor and author. If you have diabetes, you can learn how to avoid amputation by more by requesting your FREE report “No Leg Left To Stand On: The Secrets Insurance Companies Don’t Want You To Know About Diabetic Foot Amputation” at http://www.ineedmyfeet.com.
Tuesday, December 30, 2008
High Rate of Diabetes and Diabetic Related Foot Amputations
It has been reported that between 2003 and 2006, the national average diabetic amputations is 1.1 amputations per 1,000 per Medicare beneficiaries. By contrast, Pennsylvania has 1.23 lower-limb amputations per 1,000 Medicare beneficiaries. That is a rate that is about 38% higher than nearby state of Rhode Island and Michigan.
The newspaper article highlights a 77-year-old type 2 diabetic who ended up with partial foot amputation. The story explains that the gentleman had a bone spur and persistent diabetic foot ulcerations, which lead to an infection. Because of the spread of the infection, it was necessary to perform a partial foot amputation in an attempt to save his leg. He had been borderline diabetic for about 10 years prior to the amputation. Amputation was followed by a stay in a nursing home, where he received powerful antibiotics.
Unfortunately many Southern states actually have even worse rates of amputations than Pennsylvania. Geography is the not the only contributing factor. It was also reported that African-Americans nationwide have a risk that is about four times the amputation rate for Caucasians. The rate is actually nearly 7 times as bad if they live in Louisiana, South Carolina or Mississippi.
Poor diet and lack of exercise are all contributing factors to these sorts of complications related to diabetes. Patterns of diet and exercise appeared to have geographic correlation.
The Dartmouth Atlas also reveals that African-Americans nationwide have four times the amputation rate of whites, with nearly seven times the national average in portions of Louisiana, South Carolina and Mississippi. Texas actually has some of the highest rates of amputation with McAllen, Corpus Christi and Harlingon being the worst areas. These areas have imputation rates that are nearly twice the national average.
The diabetic foot partial amputee highlighted in this story credits his podiatrist with saving his legs so that he can still walk. Early detection with these sorts of complications is essential to preventing a worse amputation.
Is absolutely necessary for your doctor to check your at your visit, if you are a diabetic, any new open sore or concerning area on the foot must be checked immediately. We know that early intervention can prevent open sores, infections, and amputation related diabetes. It’s hard to believe, but true, that something as simple as ingrown toenail can lead to the sort of infection results in a diabetic amputation.
Lower limb amputations related to diabetes, are often the result of poor blood sugar control, diabetic foot neuropathy, and a compromised immune system. Unfortunately, these are not the only problems and develop diabetes. Many diabetics also develop heart disease, kidney disease and blindness.
Of all of these complications, diabetic foot ulcers, wounds, and other problems that can lead to gangrene and amputation may be the most preventable. Although there has been increasing awareness of the problems related to diabetic orders, it seems to be very slow progress in the area of actual prevention of these problems. Many new technologies do exist which can aid in the detection and early prevention of the open sores that the heat infections in amputations among diabetics.
The more traditional methods of preventing these problems include seeing a podiatrist to check the pulses in the feet in order to assess blood flow. If there is any compromise of the circulation referral to a vascular surgeon may be arranged. Often times blood flow to the feet and legs can be restored through stent placement or angioplasty. Sometimes a bypasses performed in order to restore blood flow to defeat. Checking for neuropathy, or diabetic nerve damage, is also important. Diabetic shoes are also helpful in reducing friction and shear forces to the feet that can lead to open sores.
Unfortunately, even these well-documented interventions are not available to everybody. It is well known that poverty and a lack of access to podiatrists and other healthcare practitioners can increase the rates of complications leading to diabetic foot amputation.
The worst part about all of this is that we know that once in amputation does occur, life expectancy and dropped to only about 18 months. This is often because of decreased mobility, increase risk of developing pneumonia and other health-related problems.
Source: http://www.post-gazette.com/pg/08364/938218-114.stm
Dr. Christopher Segler is an author, inventor and award winning diabetic foot specialist. He is the founder of a private consulting firm specializing in the prevention of diabetic foot amputations. If you or someone you care about has diabetes, you can learn more by simply requesting your FREE report “No Leg Left To Stand On: The Secrets Insurance Companies Don’t Want You To Know About Diabetic Foot Amputation” at http://www.ineedmyfeet.com.
Friday, December 26, 2008
Gene Therapy may be the Future in Amputation Prevention in Diabetics with Poor Blood Flow
Critical limb ischemia is a condition that results in a severe lack of blood flow to the patient’s feet and legs. This often occurs in patients with diabetes. Peripheral vascular disease and disruptions in blood flow to the feet and legs are a major cause of amputation in the United States. At present, about 70% of all amputations are related to diabetes.
When a patient has diabetes, the process of atherosclerosis which clogs the arteries happens faster. If this process goes on for long enough, critical limb ischemia can develop. Because the arteries become clogged, there is less circulation to the feet and legs.
This results in a lack of oxygen and, in a sense, starves the tissues of nutrients. Without nutrients, the tissue start to die off and ulcers (or diabetic foot sores)can develop. “The goal of gene therapy is to stimulate the growth of new blood vessels. The additional blood vessels will carry more blood into the legs, alleviating pain and healing ulcers,” one of the researchers said.
The research is presently being done at Rush University involves Phase III clinical trials which will evaluate the effectiveness of gene therapy in preventing amputations in people with critical limb ischemia.
At present there are no prescription drugs at all available which can effectively treat critical limb ischemia. Because there are so few interventions that are effective, new therapies are needed in order to prevent the sorts of amputations.
This type of gene therapy is known as angiogenesis therapy, which means growth of new blood vessels. This sort of gene therapy appears to induce the production of a protein called fibroblast growth factor (FGF-1) which stimulates the growth of blood vessels at the site of injection.
The clinical trials that are now under way will last for one year. Participants are over 50 years of age, have stable ulcerations of the skin and noninfected gangrene on a foot or leg. All have also been diagnosed with peripheral arterial disease and critical limb ischemia. The participants will receive for injections of the investigational medication or a placebo into the leg muscle a two week intervals.
It is known that about 8 million people suffer from peripheral arterial disease. In the United States, that means one out of every 40 adults. It is a very common disease. It is often underdiagnosed. Because it is so common in diabetic patients, this might provide new hope for the prevention of diabetic foot amputations.
Dr. Christopher Segler is an author, inventor and award winning diabetic foot specialist. He is the founder of a private consulting firm specializing in the prevention of diabetic foot amputations. If you or someone you care about has diabetes, you can learn more by simply requesting your FREE report “No Leg Left To Stand On: The Secrets Insurance Companies Don’t Want You To Know About Diabetic Foot Amputation” at http://www.ineedmyfeet.com.
Monday, December 8, 2008
How Can Becoming an Athlete Prevent a Diabetic Foot Amputation?
Not only can exercise such as running help a diabetic patient by changing the way that the body can use insulin, it also can help a number of other conditions.
We know that in all people, exercise can dramatically affect cholesterol levels. Hyperlipidemia or high cholesterol is one common condition affecting diabetic patients. We know that the VLDL and LDL (bad cholesterol) is lowered with exercise, while HDL (good cholesterol) is increased.
In addition, regular exercise can significantly affect a person’s blood pressure. Hypertension or high blood pressure is a common complication of diabetes. We know that regular exercise can typically reduce blood pressure by an average of 10 mm/Hg.
Obesity is another problem that is commonly associated with diabetes. Obesity alone is a major cardiovascular risk factor. It also leads to insulin resistance, further complicating diabetes. When a diabetic patient loses at least 15 to 20 pounds, fasting insulin levels can drop by 30 to 50%. As a result, there is much better blood glucose control.
Heart attacks and strokes are very common in type 2 diabetic patients. Regular aerobic activity such as walking and running have been shown to reverse the effects of increased levels of an enzyme called plasminogen activator inhibitor-1, which can in turn significantly reduce the risk of heart attack and stroke.
All of the disease processes mentioned can help clog the arteries and decrease blood flow to the legs. When this happens, you can get an open sore... it doesn't heal... it gets infected... and then you get gangrene. Once you get a diabetic foot infection with gangrene of the foot you will either get an amputation or you will die. But not to worry... it is all preventable!
With all of these possible benefits of exercise, it is understandable why any diabetic patient would (and should) embark on a program of exercise. The whole emphasis with diabetes is preventing long-term complications. Train Smart...Live Long!
Dr. Christopher Segler is an award winning diabetic foot surgeon, author and inventor. He is the founder of a groundbreaking private consulting firm that specializes in diabetic amputation prevention. If you or someone you care about has diabetes, you can learn more by simply requesting your FREE report “No Leg Left To Stand On: The Secrets Insurance Companies Don’t Want You To Know About Diabetic Foot Amputation” at http://ineedmyfeet.com.
Sunday, November 30, 2008
Diabetes and Feet...What’s the Big Deal?
Whenever I have a new diabetic patient in my practice, I always ask them if they have know anyone who had a diabetic amputation. Almost all say yes. Then I ask if they know what happened to the friend, relative or co-worker that led to them losing the leg. In most cases there is some vague mumbling about an open sore or some kind of infection, but never any details. No real clear understanding of what transpired.
Shouldn’t every diabetic know the details so this could be prevented?
With each and every new patient with diabetes, they either fully comprehend the risks of diabetes to their feet (very rare) or they have no clue (very common). With every one of these folks I feel that the one goal is to get them to understand that diabetic foot problems are optional.
Diabetes can be a tough disease to deal with. Your doctor starts telling you what to eat, telling you to exercise, lecturing about heart attacks. Then you are at home learning about blood sugar monitoring, taking medicine, pricking your finger every day. Now I gotta think about my feet too? Seems like such a hassle.
And it is.
But the good news in all of this is that everything bad that can happen to you because of diabetes is preventable. Everything. All it takes is the right learning, a little lifestyle change, and little daily effort. The goal of this article is to get you to understand the basics of how diabetes can affect your feet...so you can do something about it.
When you have diabetes you have three main problems, all working together and conspiring against you, that can lead to a diabetic foot amputation. It involves your nerves, blood flow and immune system.
When your blood sugar is high, there is a chemical reaction that directly damages the ends of the longest nerves in your body. The longest ones start in your back (where they exit the spine) and head all the way down to the toes in one long piece. Because the ends get damaged first, any nerve damage starts in the toes and gradually creeps up the foot toward the ankles.
It is always damaged at the same level in both feet. For example, if you have nerve damage (neuropathy) at the ball of the foot, the nerve damage is only in the toes. In this case the arches and heels might be fine.
Neuropathy makes it hard for you to tell if you are getting a blister or an open sore, and puts you at risk for problems. It is deceptive because you might be able to feel other things like the position of your feet, shoes and socks squeezing, but not a blister, cut or sore.
The second problem is blood flow or circulation in the feet and legs. The arteries get clogged faster when you have diabetes. If you take two people who are identical except one is diabetic, the one who is diabetic is four times more likely to have a heart attack. That is because of the increased rate of clogging up those arteries through the process called atherosclerosis. But this process happens everywhere, not just the heart. The blood vessels to the legs get plugged up too. Then when you get a sore it takes longer to heal. It is also harder for your infection fighting white blood cells to get down there.
The last problem is your immune system. When your blood sugar is high, the white blood cells (called macrophages) have a hard to time fighting off those nasty bacteria. The white macrophages find bacteria through a process called chemotaxis. It is like following a trail of chemicals to its source. This is not very effective when the blood sugar is elevated. In effect, they are lost in the dark, simply bumping around hoping stumble into some bacteria to kill. Very inefficient and not very effective.
Once they do find the bacteria they have a bigger problem. The high blood sugar prevents them from eating the bacteria. The process where the white blood cells engulf the bacteria (called phagocytosis) is essentially disabled. So they bump up against they bacteria, but can’t do anything. Imaging a great white shark with his mouth wired shut trying to eat a smaller fish for dinner. Because of all of the this, the immune system is ineffective, the bacteria continue to grow and the infection quickly gets out of hand.
So an amputation goes something like this. You get a little nerve damage, can’t feel a blister starting, and it pops. Just like that, you have an open sore. Your blood flow is a little sluggish and takes a long time to heal. Then it gets infected while it is trying to heal. If you blood sugar is high, all of those sharks are wandering around in the dark, mouths wired shut, and the infection spreads.
If it spread enough, one of the bones gets infected. And a bone infection is the kiss of death for the diabetic foot. The only reliable way to heal a bone infection in an adult diabetic is to remove the infected bone. And that is where the amputation begins.
The moral of the story is watch your blood sugar, and your nerve damage will never get any worse. If you walk 30 minutes a day, fives days a week, your blood flow will never get any worse. If you have any nerve damage, you need close monitoring by a diabetic foot expert. If you ever get an any open sore, blister or ingrown toenail it is an emergency...no joke. Get that foot checked out or it might chopped off!
Dr. Christopher Segler is an award winning diabetic foot surgeon, author and inventor. He is the founder of a groundbreaking private consulting firm that specializes in diabetic amputation prevention. If you or someone you care about has diabetes, you can learn more by simply requesting your FREE report “No Leg Left To Stand On: The Secrets Insurance Companies Don’t Want You To Know About Diabetic Foot Amputation” at http://www.ineedmyfeet.com.
